Chininum Sulphuricum. (Chininum Sulfuricum.)

Sulphate of Quinine or Chinin. C20H24N2O2, H2SO7 + 7H2O.

One of the earliest provings was that by A. Noack, in 1839, Journal fr Arzneimittellehre, vol. ii, p. 379, who also proved Cinchoninum sulfuricum, in 1842, Hygea, vol. xvi. For other provings see Encyclopaedia, vol. iii.

The pernicious and dangerous effects of crude doses of this drug, given in excess, are too well known to need mention. When indicated, as this remedy often is, in the worst forms of intermittent, there is more safety and reliability to be found in the use of the potencies, even the higher, which act promptly and well, than in the use of massive doses. In the words of Dr. H. C. Allen, the author of Therapeutics of Intermittent Fever, which should be in the hands of every homeopathic practitioner: “There is a wide difference between suppressing and curing a fever paroxysm, or any other disease; the homeopath can and ought to cure, not 'break up' the chill, 'suppress,' or 'cover up' the disease.”

- Intermittent cephalalgia, Frank, vol. 2; Periodical suborbital neuralgia, Escallier, N. A. J. H., vol. 13, p. 385; Periodical supraorbital neuralgia, R. Hughes, B. J. H., vol. 26, p. 131; Intermitting supraorbital neuralgia, Frank, vol. 3; Intermittent ophthalmia, 3 cases, Frank, vols. 1 and 3; Eye and Ear Symptoms, Scarlatina, E. W. Berridge, A. J. H. M. M., vol. 4, pp. 90-95; Tinnitus, Winslow, H. M., p. 121; Intermittent prosopalgia, 2 cases, Frank, vol. 1;[The same author mentions thirteen cases of cholera, giving a careful analysis of symptoms, treated, however, with Chin. sulph. in conjunction with Opium, which preparation was also used successfully as a prophylactic in two epidemics. These cases are not included in our arrangement, on account of the compound prescription. Dr. Aegidi, an old German practitioner, says: “For the precursory stage of cholera, I gave Chin. sulph., 0.01 to 0.06, one dose every evening for eight days. None of the persons thus treated were attacked by cholera. If I ever should live to see another cholera epidemic, I would give Chin. sulph. and ozonized water.”] Enlargement of spleen, 3 cases, Frank, vol. 4; Intermittent colic, Elb, Rückert's Klinische Erfahrungen, vol. 5, p. 364; Intermittent diarrhea, Rückert, K. E., vol. 5, p. 410; Intermittent uterine neuralgia, Frank, vol. 4; Menorrhagia with headache, Frank, vol. 2; Puerperal convulsions, Arnold, Rck. K. E., vol. 5, p. 660; Intermittent pulmonary hemorrhage, Frank, vol. 1; Intercostal neuralgia during convalescence from typhus, Kafka, Hirsch, Zeitschrift, 1, 123; Periodical cervical neuralgia, Escallier, N. A. J. H., vol. 13, p. 387; Sciatic neuralgia, Escallier, N. A. J. H., vol. 13, p. 387; Acute articular rheumatism, Escallier, Hom. Rev., vol. 4; Acute rheumatism, Frank, vol. 4, p. 103; Spinal irritation, Schleicher, Rck K. E., vol. 5, p. 868; Epilepsy, Frank, vol. 1; Intermittent apoplexy, Frank, vol. 2; Intermittent paraplegia, 2 cases, Frank, vol. 1; Ordinary cases of ague, B. J. H., vol. 23, p. 104; Intermittent fever, 11 cases, Rck. K. E., vol. 4, p. 895; C. H. von Tagen, A. J. H. M. E., vol. 4, p. 123; 2 cases, Watzke, Oestr. Zeit. fr Hom., vol. 2; H. V. Miller, Allen's Therapeutics of Intermittents; J. W. Routh, 3 cases, Med. Inv., vol. 10, p. 28; Escallier and Jeans, B. J. H., vol. 32, p. 723; W. H. Holcombe, U. S. Med. & Surg. Journ., 1872; Lembke, N. A. J. H., vol. 4, p. 277; Chronic intermittent fever, Anon., Med. Ind., vol. 7, p. 296; Typhus, Frank, vol. 3; Dropsy with enlarged spleen, Frank, vol. 4; Confluent haemorrhagic variola, Frank, vol. 3.

Indifference, stupid expression, vacant stare, averse to answering questions. ~ Typhus.
Great mental depression. ~ Variola.
Despondency.
Semi-consciousness, she is partly insensible to pain. ~ Spinal irritation.
Unconsciousness. ~ Puerperal convulsions.
Unconsciousness, with red face, deep and noisy respiration, pulse full and very slow, recurring every other day at same hour. ~ Intermittent apoplexy.
Decrease of imaginative faculty, with inability to remain standing.
Anxiety, downheartedness, moroseness, despondency, laziness, lassitude, and aversion to all kinds of work. ~ Cholera.
Recurrence of feeling of impending evil.
Anguish and general sweat.
Loud sobbing and weeping. ~ Spinal irritation.
Delirium all night while lying quietly on his back. ~ Typhus.
Delirium as if from intoxication, with humming in ears.
Furious delirium, with screaming and jumping out of bed.
Furious delirium at night, with great restlessness, followed by stupor in morning.
Delirium during heat.

Apathy, with stupid facial expression. ~ Typhus.
Head heavy and giddy, he wants to lie down. ~ Periodical cervical neuralgia.
Dizziness and enlarged feeling of head.
Whirling in head like a mill-wheel.
Vertigo, with buzzing in ears, difficult breathing, and sickness at stomach.

Pain in temple and forehead at noon, increasing gradually till temporal arteries throb obviously, with heat in head, tingling in ears, thirst, copious micturition, anxiety and great debility.
Frontal headache, where frontal bone verges towards top of head, a shaking pain, she feels every step, begins towards noon with chill.
Beating in vertex. ~ Scarlatina.
Violent headache, particularly on left side, with throbbing of temporal arteries.
Heaviness in head as from a cold. ~ Cholera.
Dull headache, with debility or with numbness.
Intermittent neuralgia at regular hours.
Intermittent headache, violent throbbing, with vertigo and heat in face, involuntary closing of eyelids from sheer prostration.
Headache with nausea, chilliness, cold feet, great prostration. ~ Menorrhagia.
Violent attacks of left-sided hemicrania occurring in evening.
Headache, the pain is not severe, but day after day, and week after week, the brain is one continued ache.

Sensitiveness and tightness of scalp, and soreness of roots of hair.
Distension of veins about head and neck. ~ Puerperal convulsions.

Bright lights and sparks before eyes.
Black spot, size of pin's head, about eighteen inches from right eye, and moving with eye, for some weeks.
Dimness of vision as from a net before eyes, and once as from a dark fog. ~ Typhus.
Blindness; amblyopia; amaurosis.
Can only see objects when looking at them sideways.
Great sensitiveness of eye to light, with lachrymation in full glare of light.
Disk and retina both very anemic.
Eyes staring and lustreless. ~ Spinal irritation.
Eyes lustreless and restless.
Dilatation of pupils.
Supraorbital neuralgia occurring daily.
Neuralgic twinges in supra and infraorbital nerves generally periodic in character.
Intermittent strabismus; child would squint one day and be entirely well on the next.
Conjunctiva injected, lids red and swollen, pupils contracted, lachrymation, extreme photophobia, tearing in orbit and headache, with thirst and fever; all appearing every second day.
At 12 o'clock, daily, violent paroxysms of pain in and around left eye, conjunctiva inflamed, photophobia, pupil contracted, lachrymation, pressure amel. pain; aggravation lasts until 8 P. M.
A sudden attack of violent pain above left eye, at 8 P. M., four days in succession, accompanied by slight delirium, muscular twitching and excessive sensitiveness to light and noise.
Violent stitching, throbbing pain in left eye, extending to forehead and temple, with photophobia, lachrymation, and inflamed conjunctiva, beginning at 1 P. M. daily, and lasting until 7, followed by perspiration. ~ Intermittent.
Lancinating pain under right eye, commences at 7 A. M., lasting until after 3 P. M., when it disappears, leaving a sensation within cranium as if there was water dropping.
Peculiar dryness of eyes.
Eyes close from weariness.

Violent ringing in ears during a chill.
Ringing in ears, especially noticed in left, seldom in right.
Ringing as of bells. ~ Spinal irritation.
Buzzing in ears. ~ Typhus.
Deafness from concussion of brain, especially of region of auditory nerve.
Hardness of hearing, with violent headache.
Tingling in ears, continually or only during headache, with giddiness when stooping.
(In sick:) Tinnitus, with injection of vessels along handle of malleus, with fullness in head and giddiness.

Frequent epistaxis.
Violent epistaxis of young persons.

Dull and stupid expression, with flushed face.
While writing sudden ache above left zygoma, also at temporal ridge.
Aching about left malar bone in evening.
Flushing of face, with redness of eyes and ears.
Face pale and suffering, lips and nails blue.
Very pale, anxious face. ~ Spinal irritation.
Paleness of face, violent thirst, nausea, weakness of feet with deafness when walking, and occasional sweat over whole body.
Jaundiced hue of face and conjunctivae. ~ Intermittent.
Face emaciated, stupid. ~ Typhus.
Attacks of prosopalgia, occurring at 10 A. M., 3 P. M. and 10 P. M.
Right-sided prosopalgia daily, from 7 A. M. until noon, accompanied by fever and lachrymation of right eye; the suffering parts become moist.
Facial neuralgia, morning periodicity, pains usually commence on left side, but sometimes on right side, and occasionally on both; attacks commence every morning, and continue from 7 to 12 o'clock; pains are lancinating, commence under eye, and soon extend into and around eye, causing considerable lachrymation; pains amel. by pressure.

Swelling of submaxillary region. ~ Variola.

Tongue flabby, coated white or yellow in centre, pale on margin.
Bitter taste with clean tongue.
Tongue and mouth dry; bitter taste. ~ Typhus.
Inability to pronounce names, and slowness of sense.

Thirst during chill and apyrexia.
Excessive thirst, with dryness of mouth and fauces, just before and during hot stage.
Real thirst mostly only during sweat.
Excessive repugnance to all food.

After eating, oppression, nausea and desire to sleep.

Nausea and loathing of food. ~ Cholera.

Pressure in pit of stomach up into throat, and pressure in stomach, agg. after drinking water. ~ Cholera.
After eating, pressure in stomach, followed by cutting in upper and middle abdominal region.
Even the slightest food causes pressure in stomach and a return of the usual symptoms.
Pain in epigastrium, agg. by pressure.
Swelling and sensitiveness of epigastrium.
Dyspepsia or cardialgia, with nausea, loathing of food, bitter eructations, bitter taste in mouth, vomiting of bile, oppression of stomach, heartburn or burning in stomach and esophagus, and feeling of constriction and pulling sensation in stomach.
Severe cardialgia.

Pain in region of liver, shortly before going to bed.
Severe pain in left hypochondrium, with shaking chill.
Pain in region of liver and spleen, on bending, taking a deep breath, or coughing. ~ Intermittent.
Painful enlargement of spleen after intermittent.
Enlargement of spleen with dropsy.

Pain in bowels, especially after eating. ~ Cholera.
Griping and tearing in abdomen, extending to chest, with pressing towards groin during menses. ~ Dysmenorrhea.
Flatulent colic of an intermittent type.
Abdomen distended. ~ Typhus. ~ Variola.
Visceral obstructions, especially engorgement of spleen and liver.
Cecal region distended, gurgling on pressure. ~ Typhus.
Relaxed condition of digestive organs of old people, under the form of dyspepsia.

Nightly diarrhea.
Diarrhea; stools watery, slimy, dark, or even blackish, having an offensive smell.
Constipation or soft stools followed by weakness.
Involuntary diarrheic stools. ~ Typhus.
Stool hard, resembling sheep dung.

Burning in urethra during urination.
The urine soon becomes turbid, with slimy flocks and a clay-colored, greasy sediment.
Urine fatty and deposits a straw-yellow, brick-dust sediment.
Involuntary urination. ~ Typhus.
Diabetes.
Albuminuria. ~ Puerperal convulsions.
Phosphates increased.
Urine loaded with lithates. ~ Supraorbital neuralgia.
Haematuria.

Menses too early and too profuse.
Violent uterine contractions sufficient to produce abortion.
Profuse menses followed by headache, with nausea, chilliness, cold feet and prostration.
Passive metrorrhagias, with diminished irritability.

Two weeks after confinement, in consequence of fright, violent uterine neuralgia, returning at same hour every afternoon, accompanied by dyspnea, small pulse, and clammy sweat on extremities, uterine region sensitive to touch.
The labor pains appear like tonic spasms, and are accompanied by convulsive twitches, unconsciousness after parturition, tetanic convulsions, in intervals convulsive action of muscles of face, eyes, etc.; want of consciousness, oppressed respiration, distended veins on head and neck, weak, rapid and intermitting pulse, and albuminuria.

Intermittent aphonia.
More or less complete loss of voice, about 4 P. M.; preceded by thirst, cough, constriction of neck, headache or neuralgia; heat in head and frequent pulse.

Can scarcely breathe from weakness. ~ Intermittent.
Respirations 28. ~ Variola.
Oppressed respiration. ~ Puerperal convulsions.
Painful sense of pressure and weight on chest. ~ Spinal irritation.
Anxiety and dyspnea with intercostal pain. ~ Typhus.
Respiration very much accelerated, abnormal rising and falling of thorax. ~ Spinal irritation.
Respiration slow and irregular.

Troublesome, moist cough. ~ Variola.

Oppression of chest.
Stitches in left side, below short ribs.
Lancinations in right half of chest, extending towards shoulder, arresting breathing, amel. by bending trunk forward.
Rattling of phlegm through entire right side of chest. ~ Typhus.
Hemorrhage from lungs; with diarrhea, fever, cold sweat and prostration.
Pain in chest during chill.

Weak, rapid and intermitting pulse. ~ Puerperal convulsions.
Pulse 100, very small, heartbeat not perceptible, sounds scarcely audible. ~ Spinal irritation.
Pulse 120. ~ Variola.
Palpitation from a little exercise.
Angina pectoris with marasmus.
Pulse: accelerated; large; full during chill and heat, weak and trembling at close of paroxysm, from fifty to sixty per minute; slow, particularly after eating; full or small, but weak and slow; frequent during heat.

Stinging, tearing pain in intercostal space, between eighth and ninth ribs, right side, extending from spine to sternum, sensitive to pressure, agg. from 4 to 7 P. M., produces anxiety and dyspnea. ~ Typhus.

Every day at about 4 P. M. violent pain in lateral muscles of neck, which appear to him to be swollen and contracted, his head is giddy and heavy, and he wants to lie down. ~ Periodical cervical neuralgia.
Sensitiveness of last cervical and first dorsal vertebrae to pressure.
Spine painful on pressure in all stages of fever paroxysm.
Three upper dorsal vertebrae are sensitive and painful to touch; pressure causes dyspnea. ~ Spinal irritation.
Periodical pain in back, returning about midnight and extending into head. ~ Spinal irritation.

Rheumatism of right shoulder.
Hands cold and cold sweat.

Sciatic neuralgia, on right side, of many weeks duration.
Acute rheumatic pain in left ankle joint after taking cold, accompanied by fever and profuse sweat.
Paralysis of lower extremities, involuntary stools and urination, occurring every other day during fever epidemic.
Paralysis of lower extremities, first occurring at 6 P. M., then half and hour earlier every day, with headache, chill, heat and sweat.
Cutting pains in feet during chill, ankles swollen.

Heaviness and aching in all limbs and especially in joints. ~ Cholera.
Stiffness of nearly all joints, right wrist and knee joint very painful and much swollen. ~ Acute rheumatism.
Acute articular rheumatism.

Wants to lie down. ~ Periodical cervical neuralgia.
Lying on back: delirium all night.
Bending: taking a deep breath or coughing; pain in region of liver and spleen.
Bending trunk forward: amel. lancinations in chest.
Stooping: giddiness.
Motion: during fever produces chilliness.
While writing: sudden ache above left zygoma and at temporal ridge.
Walking: she feels every step, frontal headache; deafness.
Exertion: the least excites sweat.
Exercise: palpitation.

Great irritation of whole body.
Extreme restlessness.
Great sensitiveness against external influences; general weakness. ~ Cholera.
Feels weak and nervous, a little exercise gives him palpitation.
Lassitude and inability to attend to his duties, has lost all zest for sport and exercise.
Debility caused by considerable losses of fluids; particularly after weakening loss of blood.
General weakness, especially of feet.
Weakness and trembling in limbs and slow pulse.
Trembling in extremities; the power of will over them seemed to be very much hampered.
Subsultus tendinum. ~ Typhus.
Twitching, or clonic spasm in limbs. ~ Spinal irritation.
Epileptic attacks returning every seven days, of short duration.
Tetanic spasms with loss of consciousness during parturition and afterwards; swollen veins on head and neck; pulse frequent, intermittent and weak; albuminuria.
Tetanic convulsions; during intervals unconsciousness.
Falling in streets.
Paralysis.
Intermittent neuralgia, pain return with great regularity.

Sleeplessness from over-stimulation of nervous system.

All night: delirium; high fever.
At night: furious delirium; diarrhea.
About midnight: pain in back returns.
In morning: stupor after delirium; facial neuralgia.
At 8 A. M.: chill.
At 10 A. M.: attacks of prosopalgia.
At 7 A. M. until noon: right-sided prosopalgia; facial neuralgia.
Towards noon: frontal headache, with chill.
At noon: pain in temple and forehead; violent neuralgia in and about left eye; chill.
Afternoon: uterine neuralgia.
At 7 A. M. until after 3 P. M.: lancinating under right eye.
At 3 P. M.: prosopalgia; shaking chill.
About 4 P. M.: cervical neuralgia.
At 4 P. M.: aphonia; chill.
From 4 to 7 P. M.: intercostal neuralgia agg.
At 6 P. M.: paralysis of lower extremities.
From 12 to 8 P. M.: neuralgia around left eye.
At 1 to 7 P. M.: stitching, throbbing in left eye.
At 8 P. M.: attack of pain above left eye.
At 10 P. M.: prosopalgia; dull; fever reaches its height.
From 6 P. M. to 4 A. M.: duration of fever.
Evening: attacks of hemicrania; aching under malar bone.

Heat: partially amel. symptoms in chill.

Paroxysms ushered in with a mere transitory, at times almost imperceptible chilly feeling, principally across shoulders and nape of neck, up and down spine, lasting for a few moments only, occurring at different times throughout day.
Chill, regular paroxysms at same hour.
Decided shaking chill at 3 P. M.
During chill, blue lips and nails, ringing in ears, pale face.
Internal chilliness.
Chilliness, especially in back, alternating with flushes of heat. ~ Cholera.
Chill every third day at 10 P. M., with intense thirst and pain in chest, followed by heat with headache, afterwards profuse perspiration; little thirst during heat and sweat.
Chill every third day at 10 A. M., with cutting pains in feet, and swollen ankles.
Quartan; chill at 4 P. M.; chilly and hot flashes in alternation for an hour, introducing a high fever, which lasts all night, with profuse sweat; during fever motion produces chilliness; constant burning in stomach; thirst satisfied for a moment with a swallow of cold water; lips covered with colorless vesicles.
Quotidian; chill at 8 A. M.; chill, fever and sweat well marked, each lasting about two hours; thirst for large draughts of cold water during whole paroxysm; nausea continually and lasting till next chill.
Fever and ague, no symptoms during apyrexia except some lassitude; paroxysms are regular and not attended with very obvious disturbances of any organ.
Distinct cold, hot and sweating stages, and perfect apyrexia.
Paroxysm anticipates about two hours each time, apyrexia clear.
Tertian; chill at 12 o'clock, M.; chill illy defined, lasting one-half hour, followed by intense fever, lasting ten hours, and terminating in scanty sweat; constant frontal headache; severe aching in limbs; heat partially relieves all symptoms, particularly the chilliness.
Fever and ague with spinal irritation, cervical and dorsal vertebrae very tender to touch, pains in loins, thighs, and lower limbs generally, convulsive movements and jerks of single muscles, slight cramps, often only of muscles of left side, dyspnea and oppression of chest, noises in ears with vertigo and dullness of mind.
Fever sets in about 6 P. M. and reaches its height about 10, continues until about 4 A. M., when sweat usually follows, with great prostration.
Fever with fullness in head, ringing in ears, together with hardness of hearing, dimness of vision, jaundiced hue of face and conjunctiva. ~ Intermittent fever.
Fever heat with delirium, fullness of head, ringing in ears, and hardness of hearing.
Strong heat over whole skin, with accelerated pulse.
Great heat of skin and dryness of mouth and fauces.
Violent heat with frequent yawning and sneezing.
Heat gradually breaks into sweat while perfectly quiet.
Profuse perspiration, especially on back and neck, when he sleeps.
Sweat easily excited through least exertion.
Sweat relieves all symptoms but headache, which is increased.
Debilitating sweat.
Typhus with great prostration, stupid facial expression, headache, diarrhea, nosebleed, alternate chill and fever, aversion to move.

Chill comes at 10 or 11 A. M. or between 3 and 10 P. M.
Paroxysms return every other day, or anticipates one to three hours every day.
Stages of chill, fever and sweat well marked and distinct.
Attacks of prosopalgia: at 10 A. M., 3 P. M. and 10 P. M.
Every other day: at same hour, unconsciousness; conjunctivitis; paralysis of lower extremities; chill.
Every seven days: epileptic attacks.
Daily: supraorbital neuralgia; stitching; throbbing pain in left eye; prosopalgia; uterine neuralgia; cervical neuralgia; paralysis of lower extremities.
At regular hours: neuralgia; chill.
Periodic: neuralgic twinges in supra and infraorbital nerves; ophthalmia; facial neuralgia; pulmonary hemorrhage; pain in back; nervous and congestive paroxysms; trismus; paraplegia.
Intermittent: neuralgia; headache; strabismus; colic; uterine neuralgia; pulse.
Anticipates about two hours each time: fever paroxysm.
Half an hour earlier every day: paralysis of lower extremities.
Four days in succession: violent pain above left eye at 8 P. M.
For some weeks: black spot before right eye.
Of many weeks' duration: sciatic neuralgia.
Day after day and week after week: continuous headache.

Left: headache and throbbing of temporal arteries; hemicrania; neuralgia around eye; pain above eye; stitching, throbbing in eye; ringing in ear; sudden ache above zygoma; aching about malar bone; pain in hypochondrium, with chill; stitches below short ribs; acute rheumatic pain in ankle joint; cramp in muscles in fever and ague, with spinal irritation.
Right: black spot before eye; lancinating under eye; ringing in ear more seldom than in left; prosopalgia, with lachrymation of eye; lancinations in half of chest; stinging, tearing in intercostal space, between eighth and ninth ribs; rheumatism of shoulder; sciatic neuralgia; wrist and knee joint pain and swollen.

Internal bad feeling, as of coming illness. ~ Cholera.
As of water dropping in cranium; as if swollen and contracted, lateral muscles of neck.
Pain: in temple and forehead; in epigastrium; in region of liver; in left hypochondrium; in bowels; in chest, during chill; in lateral muscles of neck; in right wrist and knee joint; in back; in lower limbs.
Violent pains: above left eye.
Lancinating: under right eye; in face; in right half of chest, towards shoulder.
Cutting: in upper and middle abdomen; in feet during chill.
Stitches: in left eye, forehead and temple; in left side, below short ribs.
Stinging: in intercostal space.
Tearing: in head; in orbit; in abdomen; in intercostal space.
Neuralgia: in head; in eyes; around eyes; in face; of uterus; sciatic, right side.
Rheumatic pain; in right shoulder; in left ankle joint.
Shaking pain: in frontal region.
Griping: in abdomen.
Burning: in stomach; in urethra.
Soreness: of roots of hair.
Aching: in brain; above left zygoma and at temporal ridge; about left malar bone; in all the limbs.
Throbbing: headache; in left eye, forehead and temple.
Beating: in vertex.
Stiffness: of joints.
Pressure: in pit of stomach up into throat; in stomach; on chest.
Constriction: in stomach; of neck.
Tightness: of scalp.
Pulling sensation: in stomach.
Heaviness: in head; in all the limbs.
Numbness: with headache.
Tingling: in ears.
Heat: in head; in face.
Dryness: of eyes; of mouth and fauces.

“Debility of ganglionic nutritive fibres.”
“Builds up and prevents destruction of nerve tissue.” [Obs. “Bina and his disciples found that Chininum sulfuricum, in solutions of one to ten thousand, acts fatally to infusoria, vibriones, etc., but not on fungi of mould and on salt water ameba, prevents the fermentation of lactic acid and of alcohol, but not the diastatic action on starch and on the digestive juices; that it destroys the movements of the white blood-globules in the protoplasma, and thus prevents their emigration in inflammations; that it diminishes the quantities of urea, and diminishes and retards the change of tissue in the animal body.”]
Phthisis intestinalis, nausea, gagging, loss of appetite, distension of the abdomen, constant pressure in the umbilical region, constipation, emaciation, hectic fever and delirium.
Intermittent fever in cachectic persons by loss of blood or from continued and long prostration.
Angina pectoris, where marasmus is a prominent symptom.
Fever with regular type, complete intermissions.
Periodical recurrence of nervous and congestive “paroxysms, trismus, paraplegia, ophthalmia, pulmonary hemorrhage, etc
Diminished pulse and propelling power in arterial system, injures the muscular fibres.
Fever complicated with gastric troubles and torpidity of the bowels.
Erethism of the circulatory system.
Prostration with hyperesthesia.

Great sensitiveness against external influences. ~ Cholera.
Pressure: amel. neuralgia around left eye; amel. facial neuralgia; agg. pain in epigastrium; intercostal space sensitive; last cervical and first dorsal vertebrae sensitive; dorsal vertebrae painful; spine painful; on dorsal vertebrae causes dyspnea.
Touch: uterine region sensitive; third dorsal vertebrae painful; three upper dorsal vertebrae painful and sensitive; skin sensitive.

Inflammation of skin.
Skin flaccid and sensitive to touch.
Deadness and livid redness of skin, with formation of a gelatinous pseudo-membrane or thin superficial scurf.
Urticaria eruption over body.
Red rash over whole body, with severe stinging followed by desquamation.
Gangrenous and fetid suppurations.
Cancerous ulcers, thick, livid, humid crust, which becomes dry and black, with red, humid and finally yellowish dilated margins.
Recommended in plague, by Lorbacher.
Sudamina and red spots in typhus.
Confluent smallpox, eruption hemorrhagic; pulse 120, respiration 28, abdomen distended but painless, submaxillary region swollen, moist, troublesome cough, great mental depression.

Cachectic persons weakened by loss of blood.
Suits weakly, florid, sanguine and nervous constitutions.
Boy, aet. 10; enlargement of spleen.
A boy, aet. 13; epileptic attacks.
A boy, aet. 13; intermittent paralysis of lower limbs.
Boy, aet. 15, growing very fast, and undergoing changes incident to puberty; lassitude.
Young P., aet. 16, jeweler; periodical cervical neuralgia.
A youth, aet. 17; enlargement of spleen.
A young lady, inclined to hysteria.
A robust brunette, aet. 23; spinal irritation.
Woman, aet. 24, nervo-sanguineous temperament; intermittent fever.
Mrs. A., aet. 25, blue eyes, auburn hair, mirthful temperament; chronic intermittent.
A woman, aet. 26; intermittent cephalalgia.
A primipara, aet. 28, lymphatic, chlorotic; puerperal convulsions.
A woman; intermittent paraplegia.
A woman, two weeks after confinement; intermittent uterine neuralgia.
A woman, in first month of pregnancy; epileptiform spasms.
A very sensitive lady, in seventh month of pregnancy, subject to hysteria; intermittent ophthalmia.
A weakly, hectic woman, mother of four children, pregnant; diarrhea, with night sweats.
Plethoric woman, aet. 30; intermittent apoplexy.
A young soldier, of middle stature, good constitution and sanguine temperament; typhus.
A man, of plethoric habit; intermittent prosopalgia.
Two men, with general dropsy and enlarged spleen.
Man, aet. 30, bilious temperament; intermittent fever.
J., aet. 30, clerk; suborbital neuralgia.
A woman, aet. 31; in sixth month pregnancy; intermittent fever.
A man, aet. 34; acute rheumatism.
Mr. B., lawyer, aet. 36, during past ten years had many attacks of intermittent fever, which have been cut short by sulphate of quinia; suborbital neuralgia.
A robust man, aet. 36; intermittent ophthalmia.
Robust man, aet. 40, choleric temperament; intermittent ophthalmia.
Man, aet. 42, blonde, weakly constitution, subject to gastric troubles; typhus.
A woman, aet. 48; menorrhagia followed headache.
A woman, aet. 48; intermittent fever.
A woman, aet. 50; intermittent prosopalgia.
A weakly, short, thick-set man, aet. 50; intermittent pulmonary hemorrhage and diarrhea.
Man, aet. 59, choleric temperament, large and strong; intermitting colic.
Man, aet. 60, nervo-bilious temperament; intermittent fever.

Antidotes: Arnic., Arsen., Carb. veg., Ferrum, Hepar, Laches., Natr. mur., Pulsat.
Compare: Apis (chill at 3 P. M.), Arsen. (pyaemia, spinal irritation), Bryon. (sweat from least exertion), Carb. an. (all discharges are debilitating), Eupat. perf. (sweat relieves all symptoms but headache), Nux vom. (blue lips and nails with chill), Pulsat. (rheumatic, erratic pains), Stannum (supraorbital neuralgia), Staphis. (head gradually breaks into sweat while perfectly quiet).