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en:studie [2013/03/27 13:01] (current) pistus vet |
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Walach H, Möllinger H, Sherr J, Schneider R. "Homeopathic pathogenetic trials produce more specific than non-specific symptoms: results from two double-blind placebo controlled trials." J Psychopharmacol. 2008 Jul;22(5):543-52. -- [[http://www.ncbi.nlm.nih.gov/pubmed/18701641|http://www.ncbi.nlm.nih.gov/pubmed/18701641]] | Walach H, Möllinger H, Sherr J, Schneider R. "Homeopathic pathogenetic trials produce more specific than non-specific symptoms: results from two double-blind placebo controlled trials." J Psychopharmacol. 2008 Jul;22(5):543-52. -- [[http://www.ncbi.nlm.nih.gov/pubmed/18701641|http://www.ncbi.nlm.nih.gov/pubmed/18701641]] | ||
+ | |||
+ | Bracho G et al. 2010 - "Large-scale application of highly-diluted bacteria for Leptospirosis epidemic | ||
+ | control." Homeopathy. 2010 Jul;99(3):156-66. [[http://www.ncbi.nlm.nih.gov/pubmed/20674839]] | ||
+ | |||
==== Complex meta-analysis ==== | ==== Complex meta-analysis ==== | ||
+ | |||
+ | Mathie RT et al. (2013) --//list of randomised controlled trials of homeopathy in humans, until 2011, 263 studies//-- "Randomised controlled trials of homeopathy in humans: characterising the research journal literature for systematic review." Homeopathy. 2013 Jan;102(1):3-24.([[http://www.ncbi.nlm.nih.gov/pubmed/23290875]]) | ||
Bornhöft G. et al. "Effectiveness, safety and cost-effectiveness of homeopathy in general practice -- summarized health technology assessment." Forsch Komplementmed. 2006;13 Suppl 2:19-29. Epub 2006 Jun 26. -- [[http://www.ncbi.nlm.nih.gov/pubmed/16883077|http://www.ncbi.nlm.nih.gov/pubmed/16883077]] | Bornhöft G. et al. "Effectiveness, safety and cost-effectiveness of homeopathy in general practice -- summarized health technology assessment." Forsch Komplementmed. 2006;13 Suppl 2:19-29. Epub 2006 Jun 26. -- [[http://www.ncbi.nlm.nih.gov/pubmed/16883077|http://www.ncbi.nlm.nih.gov/pubmed/16883077]] | ||
+ | |||
+ | |||
+ | //__comments on Bornhöft study:__// | ||
+ | | ||
+ | //Shaw DM. The Swiss report on homeopathy: a case study of research misconduct. Swiss Med Wkly. 2012 May 31;142:w13594. [[http://www.smw.ch/content/smw-2012-13594/]] // | ||
+ | |||
+ | //Reply to Shaw DM: von Ammon K, Bornhöft G, Maxion-Bergemann S, Righetti M, Baumgartner S,Thurneysen A, Wolf U, Matthiessen PF. Familiarity, objectivity - and misconduct: Counterstatement to Shaw DM. The Swiss Report on homoeopathy: a case study of research misconduct. Swiss Med Wkly. 2012;142:w13594. [[http://www.smw.ch/content/smw-2013-13720/]] // | ||
+ | |||
+ | **Meta-analysis of financial costs** | ||
+ | |||
+ | Viksveen P, Dymitr Z, Simoens S. Economic evaluations of homeopathy: a review. Eur J Health Econ. 2013 Feb 10.([[http://www.ncbi.nlm.nih.gov/pubmed/23397477]]) | ||
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==== Effects of highly-diluted substances on animals ==== | ==== Effects of highly-diluted substances on animals ==== | ||
* __**Database of studies:**__ HomVetCR Database -- Veterinary Clinical Research-Database in Homeopathy -- //includes about 300 studies// -- [[http://www.carstens-stiftung.de/clinresvet/index.php]] | * __**Database of studies:**__ HomVetCR Database -- Veterinary Clinical Research-Database in Homeopathy -- //includes about 300 studies// -- [[http://www.carstens-stiftung.de/clinresvet/index.php]] | ||
+ | |||
+ | Clausen J et al. -- //review study, 48 studies from 1832-2009// -- "Infection models in basic research on homeopathy". Homeopathy. 2010 Oct;99(4):263-70. ([[http://www.ncbi.nlm.nih.gov/pubmed/20970096]]) | ||
Endler et al. "Treatment of lowland frogs from the spawn stage with homeopathically prepared thyroxin (10(-30))." ScientificWorldJournal. 2007 Oct 22;7:1697-702. -- [[http://www.ncbi.nlm.nih.gov/pubmed/17982565|http://www.ncbi.nlm.nih.gov/pubmed/17982565]] | Endler et al. "Treatment of lowland frogs from the spawn stage with homeopathically prepared thyroxin (10(-30))." ScientificWorldJournal. 2007 Oct 22;7:1697-702. -- [[http://www.ncbi.nlm.nih.gov/pubmed/17982565|http://www.ncbi.nlm.nih.gov/pubmed/17982565]] | ||
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Endler et al. (2010) -- //review, repeated experiments in basic research, 107 studies, 24 models// -- "Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10(-23): a bibliometric study." Homeopathy. 2010 Jan;99(1):25-36.([[http://www.ncbi.nlm.nih.gov/pubmed/20129174]]) | Endler et al. (2010) -- //review, repeated experiments in basic research, 107 studies, 24 models// -- "Repetitions of fundamental research models for homeopathically prepared dilutions beyond 10(-23): a bibliometric study." Homeopathy. 2010 Jan;99(1):25-36.([[http://www.ncbi.nlm.nih.gov/pubmed/20129174]]) | ||
+ | |||
+ | * **Animal studies** | ||
+ | |||
+ | //assumptions for study selection:// | ||
+ | |||
+ | //- use of high potencies (12CH and more)// | ||
+ | |||
+ | //- blinded conditions// | ||
+ | |||
+ | |||
+ | //__effects on physiological functions:__// | ||
+ | |||
+ | Ruiz-Vega et al. (2005)-- "Histamine at high dilution reduces spectral density in delta band in sleeping rats". Homeopathy (2005), Vol. 94(2), pp. 86-91 ([[http://www.ncbi.nlm.nih.gov/pubmed/15892488]]) | ||
+ | |||
+ | Welles et al. (2007)-- "Pretreatment with thyroxin 10(-8) and the effect of homeopathically prepared thyroxin 10(-30) on highland frogs--a multi-researcher study." Forsch Komplementärmed (2007), Vol. 14(6), pp. 353-357 ([[http://www.ncbi.nlm.nih.gov/pubmed/18219210]]) | ||
+ | |||
+ | Weber et al. (2008)-- "The effect of homeopathically prepared thyroxine on highland frogs: influence of electromagnetic fields". Homeopathy (2008), Vol. 97(1), pp. 3-9 ([[http://www.ncbi.nlm.nih.gov/pubmed/18194759]]) | ||
+ | |||
+ | de Oliviera et al. (2011)--"Mercurius solubilis: actions on macrophages". Homeopathy (2011), Vol. 100(4), pp. 228-236 ([[http://www.ncbi.nlm.nih.gov/pubmed/21962197]]) | ||
+ | |||
+ | Kiefer et al. (2012) --"Lowland amphibians - recalculation of data on effects of diluted thyroxine". | ||
+ | Int J High Dil Res (2012), Vol. 11(38), pp. 3-18 ([[http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/view/526]]) | ||
+ | |||
+ | //Negative findings:// | ||
+ | |||
+ | Velkers et al. (2005)-- "Isopathic and pluralist homeopathic treatment of commercial broilers with experimentally induced colibacillosis" Res Vet Science (2005), Vol. 78(1), pp. 77-83([[http://www.ncbi.nlm.nih.gov/pubmed/15500843]]) | ||
+ | |||
+ | Siegling-Vlitakis et al. (2009)-- "In vitro examination of potentized atropine sulfate dilutions on the contractility of the isolated rat ileum". J Altern Complement Med (2009), Vol. 15(10), pp. 1121-1126([[http://www.ncbi.nlm.nih.gov/pubmed/19824820]]) | ||
+ | |||
+ | //__effects on animal emotions:__// | ||
+ | |||
+ | Magnani et al. (2010) --"Dose-effect study of Gelsemium sempervirens in high dilutions on anxiety-related responses in mice". Psychopharmacology (2010), Vol. 210(4), pp. 533-545 ([[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877813/]]) | ||
+ | |||
+ | Bellavite et al. (2011)-- "Effects of high-dilutions in behavioural models: a commentary on critical issues, from reproducibility to plausibility". Int J High Dilution Res 2011; 10(37): 325-337 ([[http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/532/550]]) | ||
+ | |||
+ | Bellavite et al. (2012) --"Testing homeopathy in mouse emotional response models: pooled data analysis of two series of studies". eCAM (2012), Vol. Article ID 954374, pp. 1-9 ([[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324905/]]) | ||
+ | |||
+ | Heine et al. (2012) --"Assessment of homeopathic medicine Aconitum napellus in the treatment of anxiety in an animal model". Int J High Dilution Res 2012; 11(38):33-42 ([[http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/547]]) | ||
+ | |||
+ | //__effects on animal diseases and toxicological studies:__// | ||
+ | |||
+ | Clausen J et al. (2013) -- //review of placebo-controlled trials in veterinary homeopathy, from 1965- April 2012, 203 controlled, 146 randomised, 57 non-randomised, 97 placebo-controlled trials// -- "Veterinary Clinical Research Database for Homeopathy: Placebo-controlled trials." Complement Ther Med. 2013 Apr;21(2):115-20. ([[http://www.ncbi.nlm.nih.gov/pubmed/23497815]]) | ||
+ | |||
+ | Clausen J et al. -- //review study, 48 studies from 1832-2009// -- "Infection models in basic research on homeopathy". Homeopathy. 2010 Oct;99(4):263-70. ([[http://www.ncbi.nlm.nih.gov/pubmed/20970096]]) | ||
+ | |||
+ | //later or selected older studies:// | ||
+ | |||
+ | Biswas et al. (2005)--"Efficacy of the potentized homeopathic drug, Carcinosin 200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-Dimethylaminoazobenzene-induced hepatocarcinogenesis in mice". J Altern Complement Med (2005), Vol. 11(5), pp. 839-854 ([[http://www.ncbi.nlm.nih.gov/pubmed/16296917]]) | ||
+ | |||
+ | Paula Coelho et al. (2006)-- "Therapeutic and pathogenetic animal models for Dolichos pruriens". Homeopathy (2006), Vol. 95(3), pp. 136-143([[http://www.ncbi.nlm.nih.gov/pubmed/16815516]]) | ||
+ | |||
+ | Jonas et al. (2006)-- "Can homeopathic treatment slow prostate cancer growth?" Integr Cancer Ther (2006), Vol. 5(4), pp. 343-349 ([[http://www.ncbi.nlm.nih.gov/pubmed/17101763]]) | ||
+ | |||
+ | MacLaughlin et al. (2006)-- "Effects of homeopathic preparations on human prostate cancer growth in cellular and animal models". Integr Cancer Ther (2006), Vol. 5(4), pp. 362-372 ([[http://www.ncbi.nlm.nih.gov/pubmed/17101766]]) | ||
+ | |||
+ | Banerjee et al. (2007)-- "A potentized homeopathic drug, Arsenicum album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice". J Vet Med (A) (2007), Vol. 54(7), pp. 370-376([[http://www.ncbi.nlm.nih.gov/pubmed/17718811]]) | ||
+ | |||
+ | Pathak et al. (2007)-- "Supportive evidence for the anticancerous potential of alternative medicine against hepatocarcinogenesis in mice". Forsch Komplementärmed (2007), Vol. 14(3), pp. 148-156 ([[http://www.ncbi.nlm.nih.gov/pubmed/17596695]]) | ||
+ | |||
+ | Bhattacharjee et al. (2009)-- "Homeopathic drugs Natrum sulphuricum and Carcinosin prevent azo dye-induced hepatocarcinogenesis in mice". Indian J Biochem Biophys (2009), Vol. 46(4), pp. 307-318 ([[http://www.ncbi.nlm.nih.gov/pubmed/19788063]]) | ||
+ | |||
+ | Bhattacharjee et al. (2009)-- "Amelioration of carcinogen-induced toxicity in mice by administration of a potentized homeopathic drug, Natrum sulphuricum 200". eCAM (2009), Vol. 6(1), pp. 65-75 ([[http://www.hindawi.com/journals/ecam/2009/521217/abs/]]) | ||
+ | |||
+ | Goncalves de Araujo et al. (2009)-- "Effect of Mercurius solubilis on the bacteriological response in the alveolitis process in rats". Homeopathy (2009), Vol. 98(3), pp. 160-164 ([[http://www.ncbi.nlm.nih.gov/pubmed/19647210]]) | ||
+ | |||
+ | Kuzeff et al. (2009)-- "Isopathic versus enantiomeric inhibition of U-50488 HCl toxicity" Homeopathy (2009), Vol. 98(2), pp. 83-87 ([[http://www.ncbi.nlm.nih.gov/pubmed/19358960]]) | ||
+ | |||
+ | Pathak et al. (2009)-- "Combinational homeopathic therapy reduces genotoxicity and cytotoxicity in mice fed carcinogenesis". Clin Exp Hom (2009), Vol. 1(1), pp. (1-10) ([[http://www.sukulhomeopathy.com/newjournal/khuda-buksh1.pdf]]) | ||
+ | |||
+ | Viriato et al. (2009)-- "Study of high dilution of copaiba oil on inflammatory process". Int J High Dil Res (2009), Vol. 8(26), pp. 9-14 ([[http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewFile/305/380]]) | ||
+ | |||
+ | Banerjee et al. (2010)-- "Chelidonium majus 30C and 200C in induced hepato-toxicity in rats". Homeopathy (2010), Vol. 99(3)([[http://www.ncbi.nlm.nih.gov/pubmed/20674840]]) | ||
+ | |||
+ | Ghilosso-Bortolini et al. (2010)-- "Putative protective effect of Cadmium chloride high diluted solution on LLC-PK1 cell intoxicated by high concentration of this same metal". Int J High Dil Res (2010), Vol. 9(30), pp. 16-29 ([[http://www.feg.unesp.br/~ojs/index.php/ijhdr/article/viewArticle/381]]) | ||
+ | |||
+ | Banerjee et al. (2011)-- "Evidences of protective potentials of microdoses of ultra-high diluted arsenic trioxide in mice receiving repeated injections of arsenic trioxide". eCAM (2011), Vol. 2011 ([[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135423/]]) | ||
+ | |||
+ | Patil et al. (2011)-- "Modulation of arthritis in rats by Toxicodendron pubescens and its homeopathic dilutions". Homeopathy (2011), Vol. 100(3) ([[http://www.ncbi.nlm.nih.gov/pubmed/21784329]]) | ||
+ | |||
+ | Bhattacharjee, Khuda-Bukhsh (2012)-- "Two homeopathic remedies used intermittently provide additional protective effects against hepatotoxicity induced by carcinogens in mice" J Acupunct Meridian Stud (2012), Vol. 5(4), pp. 166-175 (http://www.ncbi.nlm.nih.gov/pubmed/22898065) | ||
+ | |||
+ | Mohammadi et al. (2012)-- "Homeopathic treatment for peripheral nerve regeneration: an experimental study in a rat sciatic nerve transection model." Homeopathy (2012), Vol. 101(3), pp. 141-146 ([[http://www.ncbi.nlm.nih.gov/pubmed/22818230]]) | ||
+ | |||
+ | Patel et al. (2012)-- "Toxicodendron pubescens retains its anti-arthritic efficacy at 1M, 10M and CM homeopathic dilutions." Homeopathy (2012), Vol. 101(3), pp. 165-170 ([[http://www.ncbi.nlm.nih.gov/pubmed/22818234]]) | ||
+ | |||
+ | //Negative findings:// | ||
+ | |||
+ | Almeida et al. (2009)-- "Homeopathic treatment for bone regeneration: experimental study." Homeopathy (2009), Apr;98(2):92-6. ([[http://www.ncbi.nlm.nih.gov/pubmed/19358962]]) | ||
+ | |||
+ | * **Bacterial studies** | ||
+ | |||
+ | Saha et al. (2012) -- "Phenotypic evidence of ultra-highly diluted homeopathic remedies acting at gene expression level: a novel probe on experimental phage infectivity in bacteria" Journal of Chinese Integrative Medicine (2012), Vol. 10(4), pp. 462-470 ([[http://www.ncbi.nlm.nih.gov/pubmed/22500721]]) | ||
+ | |||
+ | Das S et al. (2012) -- "Potential of the homeopathic remedy, Arnica Montana 30C, to reduce DNA damage in Escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes. Zhong Xi Yi Jie He Xue Bao. 2012 Mar;10(3):337-46. ([[http://www.ncbi.nlm.nih.gov/pubmed/22409925]]) | ||
+ | |||
+ | De A et al. (2012) -- "Potentized homeopathic drug Arsenicum album 30C inhibits intracellular reactive oxygen species generation and up-regulates expression of arsenic resistance gene in arsenine-exposed bacteria Escherichia coli" J Chin Integr Med (2012), Vol. 10(2), pp. 210-227 ([[http://www.jcimjournal.com/en/FullText2.aspx?articleID=jcim20120212]]) | ||
* **Studies on plants** | * **Studies on plants** |